Article Details

Biological Activity of Quinazoline and Their Fused-Ring Systems |

Ravish Kumar Chauhan, in Journal of Advances in Science and Technology | Science & Technology


Quinazoline and their fused-ringsystems are well known for their potential biological activity. Inspired bythis and in view of the usefulness of heterocyclic thiols as vulcanizationaccelerators, new derivatives viz. Quinazoline-2-thiols were prepared.These  were synthesized by the condensation  of 2-[isothiocyanato(substituted phenyl)methyl]-3,4-dihydronaphthalene-1(2H)-one with primaryaromatic  amines. All the preparedcompounds have been characterized by elemental analysis, IR and mass spectroscopy.