Article Details

Synthesis characterisation and Biological Studies of Pyridazine Analogues | Original Article

Sheetal Thakur*, Rajesh Kumar Kushwaha, in Journal of Advances and Scholarly Researches in Allied Education | Multidisciplinary Academic Research

ABSTRACT:

The findings from a single treatment were presented in the form of a mean graph showing the percentage growth of treated cells. For the One-dose test, the reported value reflects an increase from the baseline number of cells and is also expressed as a percentage relative to the no-drug control.The - NH group that is present in benzimidazole is capable of forming salts due to its ability to be both highly acidic and mildly basic at the same time. The product demonstrated quick prototropictautomerism rather than isomerism. occurs when the group that is connected to the nitrogen atom in the first position is bigger than the hydrogen atom in this case, tautomerism does not occur. In the current research work, we have synthesised new derivatives of 4H- pyrazolo[3,4-d]pyrimidine by reacting 3-amino-5- (methylthio)-1H-pyrazole-4- carboxamide and various benzaldehyde with propyl phosphonic anhydride (T3P, 50 Ethyl acetate) in acetonitrile solvent at reflux temperature. A result of 0 indicates that there was no overall increase during the duration of the trial. A number of -40 would indicate a lethality level of 40. A number of -100 signifies all cells are dead. The data from a single dosage mean graph is already accessible for comparative examination.