A Study of Pyrazole Derivative Synthesis and Characterization

Published in Journal

Journal of Advances in Science and Technology [JAST] (Vol:15/ Issue: 1) DOI: 10.29070/JAST
Authors: Mukta Sharma*,
Subjects: Science & Technology

Year: Mar, 2018
Volume: 15 / Issue: 1
Pages: 154 - 159 (6)
Publisher: Ignited Minds Journals
Source:
E-ISSN: 2230-9659
DOI:
Published URL: http://ipublisher.in/p/305313
Published On: Mar, 2018

Article Details

A Study of Pyrazole Derivative Synthesis and Characterization | Original Article

Mukta Sharma*, in Journal of Advances in Science and Technology | Science & Technology

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ABSTRACT:

Pyrazoles and their variously substituted derivatives are important biological agents and substantial amount of study activity has been directed towards this class. In particular, they are used as antitumor, antibacterial and antifungal, antiviral, antiparasitic, antitubercular, insecticidal, anti-inflammatory, anti-diabetic, anesthetic and analgesic agents. A four new 1,3,5-trisubstituted pyrazole derivatives (2a-d) were synthesized from the reaction of corresponding 1,3-diaryl-2-propene-1-one compounds (1a-d) with phenyl hydrazine in glacial acetic acid. The pyrazole derivatives were divided for their antimicrobial activities in contradiction of several bacterial species and candida albicans.