Fungal Infection of Candida Albicans: Genetics, Dimorphism and Pathogenicity

Published in Journal

Journal of Advances in Science and Technology [JAST] (Vol:6/ Issue: 12) DOI: 10.29070/JAST
Authors: Dr. Mahesh Sah,
Subjects: Science & Technology

Year: Feb, 2014
Volume: 6 / Issue: 12
Pages: 0 - 0 (0)
Publisher: Ignited Minds Journals
Source:
E-ISSN: 2230-9659
DOI:
Published URL: http://ipublisher.in/p/2700
Published On: Feb, 2014

Article Details

Fungal Infection of Candida Albicans: Genetics, Dimorphism and Pathogenicity |

Dr. Mahesh Sah, in Journal of Advances in Science and Technology | Science & Technology

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ABSTRACT:

Candida albicans a dimorphic fungus that causes severeopportunistic infections in humans. Recent advances in molecular biologytechniques applied to this organism (transformation systems, gene disruptionstrategies, new reporter systems, relatable promoters) allow a better knowledgeof both the molecular basis of dimorphism and the role of specific genes inCandida morphogenesis. These same molecular approaches together with thedevelopment of appropriate experimental animal models to analyze the virulenceof particular mutants, may help to understand the molecular basis of Candidavirulence.