Polymeric Reagents Offer a Variety of Unique Benefits.Intra-Molecular Reactions, Such As the Cyclization of Peptides or Dieckmanncyclizations Can Be Applied By Attaching the Reactive Molecules at Distantpoints Along a Polymer Chain. In Contrast, If the Reactive Molecules Aresecured In Close Approprinquity on a Polymeric Support Then Intermolecularreactions Take Place As Illustrated For a Ketone Synthesis. Besides Suchproximity Effects, Mutual Effects Can Also Be Oppressed, E.G. In Theaccumulation of a 2:1 Complex of a Crown Ether and an Alkali Metal Ion. Thehydrolysis of an Ester With Polyvinyl Imidazole Gives a Wide Demonstration Ofhydrophobic Intercommunications. the Simple Dialysis of Polymer-Bound Andlow-Molecular Compounds By Filtration Is Another Significant Benefit.