Every Year, Millions of Infants Throughout the Globe Are Not Breathing During Birth and Require Infant Resuscitation. Only If the Medical Personnel In the Delivery Room Is Well-Versed In Infant Resuscitation Can They Guarantee the Safety and Health of the Newborns. the Purpose of This Study Was To Assess Nurses' Knowledge In Newborn Resuscitation. a Descriptive Cross-Sectional Study Was Carried Out To Evaluate Nurses' Knowledge of Newborn Resuscitation Procedures. the Selection of Participants Was Carried Out In a Random Fashion, Much Like a Census. the 86 Nurses Who Worked In the Maternity Unit At The Parsa District Ngo Were Questioned Using a Semi-Structured Interview Schedule, and Their Performance Was Rated Based on Observations. the Findings Showed That 93 of Respondents Had Inadequate Knowledge (85 Score) and 90.7 Had Inadequate Skills (85 Score) When It Came To Newborn Resuscitation. Working Experience, Specifically In a Maternity Unit, and Completion of Infant Resuscitation Training Both Correlate With Increased Skill When It Comes to Resuscitating Neonates (P=0.034, P=0.028, and P=0.001, Respectively). Knowledge and Ability Scores on the Same Question Concerning Baby Resuscitation Were Shown to Have a Strong Correlation In This Study (P0.0018). In This Study Discuss Effectiveness of Hands-On Training Programme Association With Pre-Test Knowledge Score and Selected Demographic Variable Regarding Basic Neonatal Resuscitation Among Nurses.