As a Result of Challenges Associated With Swallowing, There Has Been a Recent Uptick In The
Demand For Tablets That May Be Dissolved In the Mouth. This Trend Has Been Observed Particularly Among
Elderly and Juvenile Patients. Cinnarizine, an H1-Receptor Antagonist, Is a Common Medication For
Treating Motion Sickness, Vomiting, and Vertigo. Cinnarizine Tablets That Dissolve In the Mouth Were Made
Using Effervescent, Superdisintegrant Addition, and Sublimation Processes Respectively. Since The
Superdisintegrant Addition Method Resulted In the Quickest Disintegration Time, It Was Selected For Further
Study. For the Next Nine Batches, We Diluted Model Drug, Carboxymethylcellulose Salt, and L-Hpc To
Various Concentrations (B1-B9) the Range of Strengths Covered Was from 5 to 10.It Was Determined
How Much Each Formulation Varied In Weight, How Hard It Was, How Friable It Was, How Much Active
Ingredient It Contained, How Long It Took to Disintegrate In Vitro, How Long It Took to Wet In Vitro, and How
Well It Dissolved In Vitro. the Formulation That Contained 10 L-Hpc Exhibited a Shorter Disintegration
Time of 25.3 Seconds and a Shorter Wetting Time (29.1 Seconds). In-Vitro Dissolving Tests Demonstrated
That the Whole Dose of Medication Was Released Within Just Six Minutes.