Biological Activity of Quinazoline and Their Fused-Ring Systems |
Quinazoline and their fused-ringsystems are well known for their potential biological activity. Inspired bythis and in view of the usefulness of heterocyclic thiols as vulcanizationaccelerators, new derivatives viz. Quinazoline-2-thiols were prepared.These were synthesized by the condensation of 2-[isothiocyanato(substituted phenyl)methyl]-3,4-dihydronaphthalene-1(2H)-one with primaryaromatic amines. All the preparedcompounds have been characterized by elemental analysis, IR and mass spectroscopy.