Chemical Synthesis of Dihydropyrimidine (Dhpms) Derivatives By Biginelli Reaction Using Microwave Irradiation

Published in Journal

Journal of Advances in Science and Technology [JAST] (Vol:10/ Issue: 21) DOI: 10.29070/JAST
Authors: Divya Verma, Sarita Parmar, Srinivasa Rao Jetti, Shubha Jain,
Subjects: Science & Technology

Year: Feb, 2016
Volume: 10 / Issue: 21
Pages: 0 - 0 (0)
Publisher: Ignited Minds Journals
Source:
E-ISSN: 2230-9659
DOI:
Published URL: http://ipublisher.in/I/a/3839
Published On: Feb, 2016

Article Details

Chemical Synthesis of Dihydropyrimidine (Dhpms) Derivatives By Biginelli Reaction Using Microwave Irradiation |

Divya Verma, Sarita Parmar, Srinivasa Rao Jetti, Shubha Jain, in Journal of Advances in Science and Technology | Science & Technology

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ABSTRACT:

A series of spirofusedheterocycles were synthesized viacondensation of cyclic ketone, aldehyde, and urea under microwaveirradiation. The microwave assisted reaction was remarkably successful and gave𝜎 symmetric spiroheterobicyclic compounds in good yields in the presence ofDecatungstodivanadogermanic acid H6GeW10V2O40⋅ 22H2O as a catalyst under solvent-freeconditions at 800C.